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王华
2023-03-07 13:24
  • 王华
  • 王华 - 教授博士生导师-安徽医科大学-个人资料

近期热点

资料介绍

个人简介

王华,1981年出生,教授、博士生导师,安徽省学术和技术带头人后备人选,青年皖江学者获得者,美国堪萨斯大学医学研究中心访问学者,国家自然科学基金函审专家,现任公卫学院院长助理、毒理系常务副主任和环境毒理学安徽普通高校重点实验室常务副主任。主持国家自然科学基金3项和省级项目2项,参加国家基金重点项目1项(排第2),以通讯或第一作者发表SCI论文36篇(其中4篇2018IF>15),荣获安徽省科学技术奖(自然科学类)一等奖1项、二等奖2项以及中华医学科技奖2项,获得中国毒理学会首届优秀青年科技人才奖、中国药理学会Servier青年药理学奖、安徽青年科技奖和安徽医科大学首届十佳科技新星。教学方面,主持校级青年教师教学研究项目1项,指导大学生国家级创新训练项目1项,曾获中国毒理学会全国教学竞赛二等奖和安徽医科大学优秀教案评比一等奖,获得安徽医科大学最受欢迎教师提名奖、校级优秀教师和校级教坛新秀,主编《实验技术中的惑与获》(人卫版),参编教材/著作7部。2.教育经历2011/09–2015/06,安徽医科大学,儿少卫生与妇幼保健学,博士研究生2006/09–2009/06,安徽医科大学,卫生毒理学专业,硕士研究生1999/09–2004/06,安徽医科大学,预防医学专业(妇幼保健学方向),本科生3.工作经历2017.12–至今安徽医科大学,教授、博士生导师2016/09–2017.08,美国堪萨斯大学医学中心,药理学与毒理学系,访问学者2012/09–至今,安徽医科大学,公共卫生学院,副教授,硕士生导师2004/07–2012/08,安徽医科大学,公共卫生学院,助教和讲师4.主持与参加科研项目(1)国家自然科学基金面上项目,81973079,内质网PERK/ATF4信号调控的线粒体自噬在镉抑制胎盘孕酮合成与分泌中的作用,2020/01-2023/12,55万元,在研,主持。(2)安徽省青年皖江学者,2018.01-2020.12,50万元,在研,主持。(3)安徽省转化医学研究院科研基金项目,2017zhyx22,N-乙酰半胱氨酸和氯喹联合处理对环境应激所致胎儿生长受限的保护效应研究,2018/01-2020/12,20万元,在研,主持。(4)国家自然科学基金面上项目,81473016,胎盘内质网应激在镉诱发胎儿生长受限中的作用及其分子机理,2015/01-2018/12,70万元,已结题,主持。(5)国家自然科学基金青年项目,30901217,一氧化氮引起的Notch信号下调在细菌脂多糖致畸中的作用,2010/01-2012/12,20万元,已结题,主持。(6)安徽省高校优秀青年人才支持计划重点项目,2015,预防医学。(7)国家自然科学基金重点项目,81630084,孕期维生素D缺乏与胎儿生长受限的关联及其作用机制,2017/01-2021/12,275万元,在研,主要参加者(第2)。

研究领域

主要探讨生命早期环境有害因素暴露对胎儿发育的损害作用及其机制

近期论文

(1)Wang H, Li L, Zhao M, Chen YH, Zhang ZH, Zhang C, Ji YL, Meng XH, Xu DX. Melatonin alleviates lipopolysaccharide-induced placental cellular stress response in mice. J Pineal Res, 50(4): 418-426, 2011. (2018IF: 15.221)(2)Wang H, Ni HM, Chao X, Ma X, Rodriguez YA, Chavan H, Wang S, Krishnamurthy P, Dobrowsky R, Xu DX, Jaeschke H, Ding WX. Double Deletion of PINK1 and Parkin Impairs Hepatic Mitophagy and Exacerbates Acetaminophen-Induced Liver Injury in Mice. Redox Biol 2019; 22: 101148. (2018IF: 7.793)(3)Zhu HL, Xu XF, Shi XT, Feng YJ, Xiong YW, Nan Y, Zhang C, Gao L, Chen YH, Xu DX, Wang H(通讯作者). Activation of autophagy inhibits cadmium-triggered apoptosis in human placental trophoblasts and mouse placenta. Environ Pollut 2019; 254: 112991. (2018IF: 5.714)(4)Lu JW, Wang H(共同第一作者), Ji YL, Zhang C, Ning H, Li XY, Zhang H, Duan ZH, Zhao L, Wei W, Xu DX. Differential effects of pyrrolidine dithiocarbamate on TNF-α-mediated liver injury in two different models of fulminant hepatitis. J Hepatol, 48(3): 442-452, 2008. (2018IF: 18.946)(5)Ji YL, Wang H(共同第一作者), Meng C, Zhao XF, Zhang C, Zhang Y, Zhao M, Chen YH, Meng XH, Xu DX. Melatonin alleviates cadmium-induced cellular stress and germ cell apoptosis in testes.J Pineal Res, 52(1): 71-79, 2012.(2018IF: 15.221)(6)Wang H, Wang Q, Zhao XF, Liu P, Meng XH, Yu T, Ji YL, Zhang H, Zhang C, Zhang Y, Xu DX. Cypermethrin exposure during puberty disrupts testosterone synthesis via downregulating StAR in mouse testes.Arch Toxicol,84(1): 53-61, 2010.(2018IF: 5.741)(7)Wang H, Liu L, Hu YF, Hao JH, Chen YH, Su PY, Yu Z, Fu L, Tao FB, Xu DX. Association of maternal serum cadmium level during pregnancy with risk of preterm birth in a Chinese population. Environ Pollut 2016; 216: 851-857.(2018IF: 5.714)(8)Wang H, Hu YF, Hao JH, Chen YH, Su PY, Wang Y, Yu Z, Fu L, Xu YY, Zhang C, Tao FB, Xu DX. Maternal zinc deficiency during pregnancy elevates the risks of fetal growth restriction: a population-based birth cohort study. Sci Rep 2015; 5: 11262. (2018IF: 4.011)(9)Wang H, Liu L, Hu YF, Hao JH, Chen YH, Su PY, Fu L, Yu Z, Zhang GB, Wang L, Tao FB, Xu DX.Maternal serum cadmium level during pregnancy and its association with small for gestational age infants: a population-based birth cohort study. Sci Rep 2016; 6: 22631. (2018IF: 4.011)(10)Wang H, Hu YF, Hao JH, Chen YH, Wang Y, Zhu P, Zhang C, Xu YY, Tao FB, Xu DX. Maternal serum zinc concentration during pregnancy is inversely associated with risk of preterm birth in a Chinese population.J Nutr 2016; 146(3): 509-515. (2018IF: 4.416)(11)Ji YL, Wang H(共同第一作者), Zhao XF, Wang Q, Zhang C, Zhang Y, Zhao M, Chen YH, Meng XH, Xu DX. Crosstalk between endoplasmic reticulum stress and mitochondrial pathway mediates cadmium-induced germ cell apoptosis in testes.Toxicol Sci, 124(2): 446-459, 2011. (2018IF: 3.564)(12)Wang H, Meng XH, Ning H, Zhao XF, Wang Q, Liu P, Zhang H, Zhang C, Chen GH, Xu DX. Age- and gender-dependent impairments of neurobehaviors in mice whose mothers were exposed to lipopolysaccharide during pregnancy.Toxicol Lett, 192(2): 245-251, 2010.(2018IF: 3.499)(13)Wang H, Li J, Hao JH, Chen YH, Liu L, Yu Z, Fu L, Tao FB, Xu DX. High serum lead concentration in the first trimester is associated with an elevated risk of small-for-gestational-age infants. Toxicol Appl Pharmacol 2017; 332: 75-80.(2018IF: 3.585)(14)Zhang GB, Wang H (通讯作者), Hu J, Guo MY, Wang Y, Zhou Y, Yu Z, Fu L, Chen YH, Xu DX. Cadmium-induced neural tube defects and fetal growth restriction: association with disturbance of placental folate transport. Toxicol Appl Pharmacol 2016; 306: 79-85. (2018IF: 3.585)(15)Wang H, Li J, Zhang X, Zhu P, Hao JH, Tao FB, Xu DX. Maternal serum arsenic level during pregnancy is positively associated with adverse pregnant outcomes in a Chinese population. Toxicol Appl Pharmacol 2018; 356: 114-119.(2018IF: 3.585)

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