个人简介

教育与工作简历 2015.9-至今 美国UCLA访问学者 2010.7-至今 安徽医科大学 生命科学学院 教师 2004.9 – 2010.6 复旦大学 生命科学学院 遗传学专业 遗传学国家重点实验室 博士学位 1998.9 – 2003.6 复旦大学 上海医学院 基础医学系 医学士学位 1992.9 – 1998.6 合肥市第一中学

研究领域

膀胱癌化疗耐受相关机制的表观遗传学调控 膀胱癌肿瘤干细胞

近期论文

（1）Fengyu Zhu(#), Weiqing Qian(#), Haojie Zhang(#), Yu Liang, Mingqing Wu, Yingyin Zhang, Xiuhong Zhang, Qian Gao, Yang Li(*) （2017）“SOX2 Is a Marker for Stem-like Tumor Cells in Bladder Cancer.” Stem Cell Reports 9(2): 429–437 （2）Yu Liang(#), Fengyu Zhu(#), Haojie Zhang(#), Demeng Chen, Xiuhong Zhang, Qian Gao, Yang Li(*). “Conditional ablation of TGF-b signaling inhibits tumor progression and invasion in an induced mouse bladder cancer model.” Scientific Reports 2016,6, doi:10.1038/srep29479 （3）Yang Li(#), Hui Deng(#), Lei Lv(#), Cheng Zhang(#), Liting, Qian, Jun Xiao, Weidong Zhao, Qi Liu, Daming Zhang, Yingwei Wang, Jun Yan, Hongyu Zhang, Yinghua He, Jingde Zhu(*). “The miR-193a-3p regulated ING5 gene activates the DNA damage response pathway and promotes the multi-chemoresistance of bladder cancer.”Oncotarget 2015,6(12)：10195-10206 （4）Lei Lv(#), Yang Li(#),Hui Deng(#), Cheng Zhang(#), Youguang Pu, Liting, Qian, Jun Xiao, Weidong Zhao, Qi Liu, Daming Zhang, Yingwei Wang, Hongyu Zhang, Yinghua He, Jingde Zhu(*). ” MiR-193a-3p promotes the multi-chemoresistance of bladder cancer by targeting the HOXC9 gene.” Cancer Lett. 2015 Feb 1;357(1):105-13. （5）Hui Deng(#), Lei Lv(#), Yang Li(#), Cheng Zhang(#), Fang Meng, Youguang Pu, Jun Xiao, Liting Qian, Weidong Zhao, Qi Liu, Daming Zhang, Yingwei Wang, Hongyu Zhang, Yinghua He, Jingde Zhu(*). “The miR-193a-3p regulated PSEN1 gene suppresses the multi-chemoresistance of bladder cancer.” Biochim Biophys Acta. 2014 Dec 24;1852(3):520-528 （6）Hui Deng(#), Lei Lv(#), Yang Li(#), Cheng Zhang(#), Fang Meng, Youguang Pu, Jun Xiao, Liting Qian, Weidong Zhao, Qi Liu, Daming Zhang, Yingwei Wang, Hongyu Zhang, Yinghua He, Jingde Zhu(*). “miR-193a-3p regulates the multi-drug resistance of bladder cancer by targeting the LOXL4 gene and the Oxidative Stress pathway.” Molecular Cancer 2014 Oct 14;13:234 （7）Lv L(#), Deng H(#), Li Y(#), Zhang C(#), Liu X(#), Liu Q, Zhang D, Wang L, Pu Y, Zhang H, He Y, Wang Y, Yu Y, Yu T, Zhu J(*). ”The DNA methylation-regulated miR-193a-3p dictates the multi-chemoresistance of bladder cancer via repression of SRSF2/PLAU/HIC2 expression.” Cell Death Dis. 2014 Sep 4;5:e1402. doi: 10.1038/cddis.2014.367.