个人简介

蔡亦红，副教授，卫生检验和检疫学系，公共卫生学院，安徽医科大学。教育经历2010–2014免疫学，博士学位，安徽医科大学2003–2006微生物学，硕士学位，安徽医科大学1998–2003临床医学，学士学位，皖南医学院工作经历2018.9-2019.9访问学者，OaklandUniversity，Michigen，美国2015.6-2015.12访问学者，ImmunologyFrontierResearchCenter,OsakaUniversity,日本2006-present副教授，卫生检验和检疫学系，公共卫生学院，安徽医科大学，中国主持基金：1.国家自然科学基金面上项目(NSFC)(No:81572801),AntitumoreffectofToxoplasmapolymorphiceffectorGRA15ⅡinHCCthroughregulationofmacrophagepolarization,2016.1-2019.12(ongoing)2.国家自然科学青年基金(NSFC)(No:81101272),MitochondrialapoptosisthroughanovelSTAT3-miR-17s-BimpathwayinToxoplasmainfectedhostcells2012.1-2014.12.(completed)

近期论文

1. Li Y, Poppoe F, Chen J, Yu L, Deng F, Luo Q, Xu Y, Cai Y*, Shen J*. Macrophages Polarized by expression of Toxogra15Ⅱ inhibit growth of hepatic carcinoma，Frontiers in Immunology.(2017);8:137.2. Cai Y, Shen J*. Modulation of host immune responses to Toxoplasma gondii by microRNAs，Parasite Immunology.(2017);39:e12417.3. Zhang X, Su R, Cheng Z, Zhu W, Li Y, Wang Y, Du J, Cai Y, Luo Q, Shen J, Yu L. A mechanistic study of Toxoplasma gondii ROP18 inhibiting differentiation of C17.2 neural stem cells. Parasites & Vectors. (2017),23;10(1):585.4. Gan X, Zhang X, Cheng Z, Chen L, Ding X, Du J, Cai Y, Luo Q, Shen J, Wang Y, Yu L. Toxoplasma gondii inhibits differentiation of C17.2 neural stem cells through Wnt/β-catenin signaling pathway.Biochem Biophys Res Commun. (2016); 22;473(1):187-193.5. Zhang Q, He L, Kong L, Zhang Y, Chen H, An R, Wang L, Wang W, Xu X, Zhang A, Cai Y, Li M, Wen H, Luo Q, Shen J. Genotype-Associated Arginase 1 Expression in Rat Peritoneal Macrophages Induced by Toxoplasma gondii.J Parasitol. (2015 );101(4):418-23. 6. Lanting K, Qian Z, Jing Chao, Huiqin W, Yihua Z, He Chen, Faustina P, Aimei Z, Xiucai X, Yihong C, Min L, Qingli Luo, Linjie Z, Jilong S*. Polarization of macrophages induced by Toxoplasma gondii and its impact on abnormal pregnancy in rats. Acta Tropica. (2015)143:1-7. 7. Yi-Hong Cai, He Chen, Xu-Wei Mo, Yuan-Yuan Tang, Xiucai Xu, Aaimei Zhang, Zhao-Rong Lun, Fang-Li Lu,Yong Wang, and Ji-Long Shen*. Toxoplasma gondii inhibits apoptosis via a novel STAT3-miR-17–92-Bim pathway in macrophages. Cellular Signalling. (2014)26:1204-1212. 8. Yi-Hong Cai, He Chen, Lei Jin, Yibo You and Jilong Shen*. STAT3-dependent transactivation of miRNA genes following Toxoplasma gondii infection in macrophage. Parasites & Vectors. (2013):356-365. 9. Yi-hua Zhang, He Chen, Ying Chen, Lu Wang, Yi-hong Cai, Min Li, Hui-qin Wen, Jian Du, Ran An, Qing-li Luo, Xue-long Wang, Zhao-Rong Lun, Yuan-hong Xu and Ji-long Shen*, Activated microglia contribute to neuronal apoptosis in Toxoplasmic encephalitis. Parasites & Vector.( 2014)7:372-383. 10. Huo XX, Wang L, Chen ZW, Chen H, Xu XC, Zhang AM, Song XR, Luo QL, Xu YH, Fu Y, Wang H, Du J,Cai YH, Lun ZR, Lu FL, Wang Y, and Shen JL*. Preventive effct of pidotimod on reactivated toxoplasmosis in mice.Parasitol Research. (2013)112:3041-3051.11. Liu TT, Zhang Q, Liu LL, Xu XC, Chen H, Wang H, Kong LT, Wang WW, Cai YH, Zhang AM, Li M, Yu L, Du J, Wang XL, Luo QL, Lun ZR, Wang Y, andShen JL*. Trophoblast apoptosis through polarization of macrophages induced by Chinese Toxoplasma gondii isolates with different virulence in pregnant mice. Parasitol Research. (2013)112:3019-3027.12. Zhang AM, Shen Q, Li M, Xu XC, Chen H,Cai YH, Luo QL, Chu DY, Yu L, Du J, Lun ZR, Wang Y, Sha Q and Shen JL*. Comparative studies of macrophage-biased responses in mice to infection with Toxoplasma gondii ToxoDB #9 strains of different virulence isolated from China.Parasites and Vectors. (2013)6:308-318. 13. Liu L, Liu T, Yu L,Cai Y, Zhang AM, Xu XC, Luo QL, Hu YS, Song WJ, Lun ZR, Lu FL, Wang Y, and Shen JL*, Rrop2186-533:A novel peptide antigen for detection of IgM antibodies against Toxoplasma gondii. Foodborne Pathogens & Disease. (2012)9:7-12.